49ers vs. Panthers odds, picks, line, how to watch, live stream: Model reveals 2022 Week 5 NFL predictions

The Carolina Panthers (1-3) will host the San Francisco 49ers (2-2) as part of Week 5 NFL programming on CBS and Paramount+. The Niners are seeking their first win on the road and their first win outside of the NFC West, but put on an impressive display against the Rams last Monday night. Meanwhile, this will be Carolina’s fourth home game in its first five weeks, but it has only won one of those contests so far. You can stream the game in select markets on Paramount+, which you can try free for 30 days with promo code NFLONCBS.

Kickoff for Panthers vs. 49ers is scheduled for 4:05 p.m. ET from Bank of America Stadium in Charlotte, NC. Caesars Sportsbook lists San Francisco as the six-point favorite on the latest 49ers vs. Panthers odds, while the over/under for the total points is 40. In select markets, Sunday’s matchup can be seen live on CBS and live on Paramount+ Streamed with their must-have premium plan, which you can try for free with promo code NFLONCBS.

Paramount+ now has membership tiers so you can watch your local NFL on CBS matches and more. The premium plan costs $9.99 per month and lets you watch your local CBS live stream, including many sports like SEC on CBS, NFL on CBS, and the PGA Tour, ad-free, on-demand, and with the ability to add episodes to the Download Offline Viewer. Get 30 days totally free until the end of October with promo code NFLONCBS, so sign up here now.

How to watch 49ers vs. Panthers

  • Date Panthers vs. 49ers: Sunday October 9th
  • Panther vs. 49ers time: 4:05 p.m. ET
  • Panthers vs. 49ers TV Network: CBS
  • Streaming Panthers vs. 49ers: Paramount+ (30 Days Free with promo code NFLONCBS)
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Week 5 NFL picks for 49ers vs. Panthers

Before you tune in to Sunday’s showdown, you need to check out SportsLine’s advanced computer model’s NFL picks. The model, which simulates every NFL game 10,000 times, has won nearly $7,000 for $100 players with top-tier NFL picks since its inception. The model kicks off Week 5 of the 2022 NFL season with an incredible 140-105 run of top-flight NFL picks that stretches back to the 2017 season.

The model has also ranked in the top 10 on NFLPickWatch for four of the last six years in direct NFL picks, beating more than 94% of CBS Sports football pick ’em players four times in that span. Whoever followed it is way up.

In Panthers vs. 49ers, the model supports the Under. The 49ers have conceded the fewest points and yards and held opponents to just 2.9 yards per carry, the lowest mark in the league. They’ve also conceded an NFL low of two passing touchdowns.

Carolina doesn’t have the type of offense to pierce San Francisco’s suffocating defense as the Panthers rank last on offense overall. They have the fewest first downs in the NFL and rank last in third-down conversion percentage because most of their drives end in punts rather than points. Carolina has not managed to rush for 300 yards in any game, while San Francisco has yet to allow an opponent to rush for 300 yards. The under for these teams has a combined 7-1 record and the model continues that trend with the under hitting in almost 60% of the simulations. Maybe you can stream the game here.

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How to Watch the NFL Live on CBS

Now that you know what to choose, you can watch your live local NFL games on CBS on Paramount+ on any device. Use code NFLONCBS to get 30 days free. Visit Paramount+ now to stream your local CBS sporting events live, including the NFL, SEC on CBS and more.

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