NFL odds Week 2: How to bet Colts-Jaguars, pick

That Indianapolis Colts will travel south to play those Jacksonville Jaguars for one of Sunday’s midday games, with both teams aiming for their first win of the season.

week 1 of NFL Season was not good for the Colts where there was no decisive winner between them and the Houston Texans. Matt Ryan threw for 352 yards and a touchdown but threw a costly interception.

Trevor Lawrence and the Jaguars had a tough time against the Washington Commanders. Although Lawrence threw for 275 yards and one touchdown, Jacksonville’s defense allowed Washington’s Carson Wentz to throw for over 300 yards and four touchdowns.

Here’s everything you need from a betting perspective on the Colts-Jaguars game, from point spread, moneyline, total over/under and expert picks (odds via FOX Bet):

TIED TOGETHER: Week 2 rows, odds

Indianapolis Colts @ Jacksonville Jaguars (1 p.m., CBS)

Point distribution: Indianapolis -4 (Colts prefer to win by more than 4 points, otherwise Jaguars cover)
money line: Colts -213 favorites to win (bet $10 to win $14.69 total); Jaguars +160 Win underdogs (bet $10 to win $26 total)
Total score over/under: Both teams scored 41.5 points together

FOX Sports Betting Analyst’s Picks Jason McIntyre:

The Colts put on 517 yards of offense in a 20-20 draw with the lower Texans and needed 17 points in the fourth quarter to force overtime. On the surface, it’s a poor result for the Colts, but a closer look reveals an impressive offensive performance with six drives inside Houston’s 30-yard line. But they only got two touchdowns from it when Indy went 2-for-5 in the red zone. They would have lost the game if Houston hadn’t gone ultra-conservative.

Jacksonville was the better team against Washington, registering 6.2 yards per game (YPP) and getting into the red zone five times. Between a dropped TD pass from Travis Etienne, 13 penalties, a missed field goal and a failed two-point conversion, it was a chaotic opener on the road.

Now Jacksonville is coming home with a slower track and temperatures that should be in the high 80s. The Jaguars spoiled the Colts’ 2021 season in Week 18 by knocking Indianapolis out of the playoffs, and they also defeated Buffalo in Jacksonville.

Take the points and hope the Jaguars don’t let cornerback Tyson Campbell (cooked to two TDs by Jahan Dotson) be paired with Michael Pittman (nine catches, 121 yards in Week 1) too often.

SELECT: Jaguars (+4 on FOX Bet) lose by 4 points or less (or win outright)

Are you ready for the NFL season? If so, go to FOX Bet for all your bets.

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