NFL odds Week 3: How to bet Rams-Cardinals

Los Angeles is looking to continue its recent dominance if the Aries Travel east to play at the Arizona Cardinals on Sunday (4:25 p.m. ET on FOX)

The Rams lead the all-time streak 47-29-2 and have won 10 of their last 11 games against the Cardinals.

Here’s everything you need from a betting perspective on the Rams Cardinals game, from point spread, moneyline, total over/under and expert picks (odds via FOX Bet):

Kyler Murray leads the Cardinals to a wild OT win over Raiders in Week 2 | UNDISPUTED

Kyler Murray leads the Cardinals to a wild OT win over Raiders in Week 2 |  UNDISPUTED

Kyler Murray and the Arizona Cardinals trailed 20-0 at halftime against the Las Vegas Raiders before charging back to win.

TIED TOGETHER: Sportsbook wins big in week 2

Rams @ Cardinals (4:25 p.m. ET Sunday, FOX)

Point distribution: Rams -3.5 (Rams prefer to win by more than 3.5 points, otherwise Cardinals cover)
money line: Rams -189 favorites to win (bet $10 to win $15.29 total); Cardinals +145 win underdogs (bet $10 to win $24.50 total)
Total score over/under: Both teams scored 48.5 points together

The Rams have been 11-3 against the spread (ATS) and 11-3 (SU) against the Cardinals since 2015, with the over/under (O/U) being 7-7.

The Rams have gone 18-12 ATS and 19-11 SU against NFC West opponents under coach Sean McVay since 2017, with the Underman scoring in 16 of those games in the O/U.

The Rams are 10-5 ATS and 10-5 SU against NFC West opponents under McVay, with eight of those games being overhit.

The Cardinals have lost to the Rams seven straight times at home, most recently by a 31-14 loss on November 9, 2014, when the Rams played in St. Louis.

The Cardinals have been home underdogs since 2019 under coach Kliff Kingsbury at 5-5 ATS and 3-6-1 SU, with the overhit surpassing seven times.

The Cardinals are 19-9-1 ATS and 15-13-1 SU as underdogs under Kingsbury, while the O/U go 14-14-1.

FOX Sports Betting Analyst’s Picks Geoff Schwartz:

Two overwhelming teams face each other in the desert.

The Rams are 1-1 but had to fend off a lively Falcons team who were 31-10 down early in the fourth quarter but took the lead in the final two minutes before losing 31-25.

Smoked out by the Chiefs in Week 1, Arizona needed a historic overtime comeback to beat the Raiders after going 20-0 at halftime.

At two weeks, the Cardinals and Rams are ranked 28th and 29th in team efficiency, respectively, with the Cardinals burdened with defense at 30th and the Rams with special teams at 32nd.

When two teams seem equal on paper, I grab the points, especially if I get the three plus the hook. There is some concern with this bet because Sean McVay’s Rams dominated the Cardinals and went straight ahead 10-1.

However, that number for the Cardinals is too juicy not to bet on.

Choose: Arizona (+3.5 on FOX Bet) loses by less than 3.5 points (or wins outright)

Are you ready for the NFL season? If so, go to FOX Bet for all your bets.

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