NFL odds Week 6: How to bet Jaguars-Colts, pick

The Jacksonville Jaguars (2-3) took on the Indianapolis Colts (2-2-1) in Week 6.

The Jags suffer a disappointing 13-6 loss to the Houston Texans while the Colts beat the Denver Broncos 12-9 in their own low-scoring affair.

Here’s everything you need to know about NFL odds for Sunday’s matchup between Jacksonville and Indianapolis – point spread, moneyline, overall over/under and expert picks (with all NFL odds via FOX Bet).

TIED TOGETHER: Week 6 rows, odds

jaguars at foal (1 p.m. ET Sunday, CBS)

Point distribution: Stallions 2.5 (Colts favored the win by more than 2.5 points, otherwise the Jaguars covered)
money line: Colts -138 favorites to win (bet $10 to win $17.26 total); Jaguars +110 Win underdogs (bet $10 to win $21 total)
Total score over/under: Both teams scored 41.5 points together

Findings from the FOX Sports Research Team:

• Trevor Lawrence is 3-7 against the spread (ATS) and 1-9 straight up (SU) as a starter when he’s been a career underdog on the road.
• Matt Ryan is 39-46-1 ATS and 54-32 SU as a starter if he’s a home favorite in his career.
• Jaguars have been 7-1-1 ATS and 5-4 SU against the Colts since 2018, with underscoring in 5 of those games.
• Colts are 11-15-1 ATS and 14-12-1 SU vs. AFC South opponents under Frank Reich, being under-hitting in 16 of those games.
• Colts are 4-8-1 ATS and 8-5 SU at home against AFC South opponents under Frank Reich, being flipped in 7 of those games.

Selection via FOX Sports NFL Analyst Geoff Schwartz:

The Colts are not a good football team. They are 32nd in DVOA and should not be trusted in any game. Colt’s QB Matty Ice lives up to his nickname. He’s cold as ice and completes only 63% of passes for more than 6.12 yards per attempt.

Despite losing twice in a row, the Jaguars are still the better team. You’re better as a quarterback, in the trenches and even as a head coach.

The Jaguars will have a comeback game this weekend with a win in Indy.

SELECT: Jaguars (+2.5 on FOX Bet) loses by less than 2.5 points (or wins outright)

Click here for those the latest NFL odds and everything you need in the world of sports betting at FOXSports.com and the FOX Sports App.

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